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UK government must back the Global Fund at critical time

by Justin Marsh
November 11, 2025
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In public health, complacency is the most dangerous pathogen of all. It creeps in quietly, just as progress starts to look permanent. We think a threat has been contained, a disease defeated, and we turn our attention elsewhere. But viruses do not read budget statements, and microbes do not respect borders. They exploit every gap we leave them.

That’s why talk of a reduction in Britain’s contribution to the Global Fund to Fight AIDS, Tuberculosis and Malaria should give us pause. These diseases kill millions every year. This is not a distant matter of foreign aid impacting only those in faraway lands. It is a direct question of our own health security, global stability and moral leadership.

The Global Fund is one of the most effective health partnerships in human history. Since 2002, it has helped save over 70 million lives, halving deaths from AIDS, TB and malaria worldwide. It has built diagnostic networks, strengthened local laboratories and trained community health workers across more than 100 countries. Those same systems are vital to detect new outbreaks and contain them before they spread. The UK has been at the heart of that success, something we should all be deeply proud of. This empathy represents the very best of British values.

A 20% reduction in the UK government’s contribution would not be a technical adjustment that only the accountant notices. It would see a reversal of years of progress, with real human consequences. Hundreds of thousands of preventable deaths, millions of new infections and weakened health defences in regions where pathogens emerge and spread. In an age of global mobility, that is everyone’s problem, whether you are in Pontefract or Pretoria.

I see the investment in the Global Fund akin to buying home insurance – it might not seem important or tangible at the time, but when the house burns down, you are beyond glad you paid the premium. COVID-19 reminded us that, terrifyingly, an outbreak in one part of the world can become a global emergency within a matter of weeks. The nature of the next pandemic is unknown. Vector-borne, zoonotic or drug-resistant, it may not even be a novel virus, as previously contained diseases such as TB and polio continue to rise once again. Whatever it is, the ability of other countries to detect, contain and respond swiftly will determine safety on our shores.

What makes the Global Fund so critical to global health security is that it targets the three diseases that represent the three major routes of transmission: airborne (TB), vector-borne (malaria) and blood or bodily fluid (HIV/AIDS). In doing so, it strengthens surveillance, laboratories and health infrastructure across all major transmission pathways. The result is a defence network that protects us not only from these three diseases but from whatever emerges next. We are all safer when the Fund is properly resourced.

It’s easy to frame this as aid when, in fact, it is really self-interest in its most crystallised form. Independent analyses from the Global Fund and UNAIDS show that money spent on prevention and control delivers several times that value in avoided treatment costs and crisis response. It may even be one of the safest investments HM Treasury can make. More importantly, it prevents the destabilisation that comes when health systems collapse, something we’ve seen before in regions where epidemics erode economies and governance.

The UK has long prided itself on leading by example in global health, and rightly so. We were among the first to respond to HIV in the 1980s, when stigma and fear were rife. We helped pioneer the model of multilateral funding that now saves millions each year. To cut back now, especially while co-hosting the Fund’s replenishment, would signal a retreat from that tradition of leadership just when collective resolve is most needed.

Science has handed us the tools to end these epidemics – many of which are the direct result of British innovation – from next-generation malaria nets to faster TB diagnostics and long-acting PrEP, the injectable that could revolutionise HIV prevention. It would be a tragedy not to take advantage of these breakthroughs at the very moment they become available. The UK has already committed to ending new HIV transmissions in England by 2030. That ambition, matched by our global partnerships, could help achieve something extraordinary: a world free from HIV altogether, perhaps.

When I think back to the darkest days of COVID-19, what stands out is not fear, but cooperation. Scientists in Cambridge and Cape Town, clinicians in London and Lagos, all working towards one goal. The same spirit is needed now. Given the health threats we face are global, our response must be too. Disease has no borders, but neither does scientific collaboration.

We have the science, the technology, the partnerships and the means to end AIDS, TB and malaria within a generation. It might sound bold, but we really do. But these victories only happen when nations decide they matter. Britain helped build the Global Fund because we understood that a healthier world makes for a safer world. This truth has not changed. What’s at stake now is whether we are astute enough to act upon it.

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